Most skunks can be housebroken by corner training. After they choose a corner, a litter pan with unscented litter can be placed there. If the skunk misses the litter pan, after cleanup, the area should be saturated with plain white vinegar to remove the scent, so that they will not return to that spot.
After the skunk's bathroom has been established, it can be moved about four inches a day to a different location. The skunk may or may not follow. If he doesn't, it may be necessary to give in, let the skunk have that corner, and block the view with a chair or bookcase placed in the corner or some other decorative idea.
For covered cat litter boxes, it will probably be necessary to cut a larger opening for the skunk. With any litter pan, bear in mind that regular cleaning is necessary since skunks will avoid a dirty bathroom.
Some owners have reported that their skunk could not be corner-trained or taught to use a litter box, according to Skunk Haven's Deborah Cipriani.
Letting skunks outside by themselves is risky since, like ferrets, they lack a homing instinct and can easily get lost. Descented skunks lack their most powerful defense against predators such as coyotes and foxes. Their nearsightedness also makes them susceptible to becoming roadkill.
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